Google’s Matt Cutts on the Google Webmaster Tools Help YouTube channel says that regardless of how you construct your site, either in a CSS-based layout or a Table-based layout, Google will be able to find and index your content.
Please keep this in mind that Cutts says in the video that regardless of which way your site is built Google will “try” and index it. Now with CSS-based layouts your code is cleaner and less cluttered. It’s been proven that the more cluttered your site is with extraneous code the hard it is for your Website to be indexed.
So when Cutts says it doesn’t matter and Google will “try,” don’t you think the more adventagous thing to do would be code in such a way that makes it easier for search engine robots to spider your site? I think so. What do you think? Watch the video and post your comments!